• General Application
  • Epimedium Application
    Epimedium is the traditional Chinese medicine commonly used in tonifying the kidney and strengthening yang,its application in depression and antidepressant mechanism are paid attention in recent years. Through the domestic and foreign related literatures of Epimedium antidepression,combined with clinical and basic research,its clinical application characteristics are summarized and the anti depressive mechanisms are analyzed. Herba Epimedii is used in compound compatibility for clinic application in the treatment of depression,especially in the treatment of climacteric depression and post stroke depression it has made significant effect. The mechanism mainly relates to the anti cerebral ischemia,anti free radical,anti monoamine oxidase,to control monoamine neurotransmitters and their receptors,to improve the hypothalamic pituitary adrenal( HPA) axis function and sedative and analgesic effect,protect brain cells etc.. Further research on the anti depression effect of Herba Epimedii,will provide the scientific basis for multi angle understanding of depression pathogenesis,improving the level of diagnosis and treatment of depression,and the development of antidepressant new drugs.